Ambroxan
Ambroxan (CAS #6790-58-5)—also known as Ambroxide or Ambrofix—is a premium synthetic aroma chemical celebrated for its rich, ambery, and woody scent profile reminiscent of natural ambergris. Structurally, Ambroxan is a bicyclic compound closely related to ambrein, the primary aromatic component of ambergris52.
Key Properties
| Property | Specification |
|---|---|
| Chemical Name | Ambroxide |
| Synonyms | Ambrofix, Ambroxan, Ambrox®, Ambrox Super |
| Molecular Formula | C₁₆H₂₈O |
| Molecular Weight | 236.39 g/mol |
| EC Number | 229-861-2 |
| Appearance | White crystalline powder or solid |
| Odor | Intense, warm, ambery, woody, musky |
| Purity | ≥ 99% |
| Melting Point | 75–78°C |
| Boiling Point | 311–318°C |
| Flash Point | ≥ 110°C |
| Solubility | Soluble in alcohol, insoluble in water |
| Density | ~1.0 g/cm³ |
Olfactory Profile
Scent: Warm, clean ambergris with woody, musky, and slightly animalic nuances. Ambroxan delivers exceptional radiance, volume, and a signature sweetness to fragrances, even at low dosages126.
Performance: Outstanding tenacity and diffusion, making it a pillar material in both masculine and feminine fragrances63.
Applications
Perfumery:
Used as a powerful fixative and base note in high-end fine fragrances, providing warmth, depth, and longevity to compositions.
Replaces natural ambergris for ethical and economic reasons, and is a key ingredient in many iconic perfumes235.
Cosmetics:
Incorporated into creams, lotions, and deodorants for its elegant and long-lasting ambergris-like aroma5.
Aromatherapy:
Adds a calming, grounding effect to relaxation blends.
Home Fragrance:
Used in candles, diffusers, and room sprays for a rich, persistent scent54.
Functional Perfumery:
Enhances scent retention and freshness in detergents, shampoos, fabric softeners, and other household products34.
Regulatory & Safety
IFRA Compliance: Permitted in all fragrance categories under current IFRA guidelines; no specific restrictions546.
REACH Registered: Approved for use in fragrances and cosmetics.
Toxicology: Low toxicity, non-sensitizing, and non-phototoxic at standard usage levels34.
Halal Certified: Available as a halal-certified ingredient6.
Storage & Handling
Storage: Store in a cool, dry, well-ventilated area away from direct sunlight and moisture.
Shelf Life: 24 months under recommended storage conditions5.
Handling: Avoid direct contact with eyes and skin; use protective equipment and ensure good ventilation during handling.
Ambroxan is a cornerstone of modern perfumery, prized for its ability to impart warmth, depth, and lasting elegance to fragrances, while offering exceptional stability and compatibility across a wide range of applications